Chlorpheniramine maleate as an alternative to antiemetic cyclizine

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Allergic contact dermatitis following drug rash due to chlorpheniramine maleate

Allergic contact dermatitis (ACD) is one of the common causes of facial swelling. Clinical clues for diagnosing ACD include a rash that spares the area behind the ears, nasolabial folds, and under the chin. Once clinicians suspect ACD, the substances that cause contact dermatitis should be avoided.

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Formulation and Evaluation of Medicated Chewing Gums of Chlorpheniramine Maleate

The aim of the present work is development and evaluation of Chlorpheniramine maleate medicated chewing gums and to study the influence of different plasticizers on physicochemical parameters and in vitro drug release profile. Chlorpheniramine maleate is used to relieve symptoms of allergy, hay fever and common cold. Prepared formulations are evaluated for thickness, hardness, weight variation,...

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A Case of Chlorpheniramine Maleate-Induced Hypersensitivity With Aspirin Intolerance

Antihistamines are commonly used to treat allergic disease, such as allergic rhinitis, urticaria, and angioedema. Although several previous reports describe hypersensitivity to antihistamines such as cetirizine and hydroxyzine, documented cases of chlorpheniramine hypersensitivity are extremely rare. Here, we report the case of a 45-year-old Korean woman who presented with urticaria after inges...

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Controlled trial of terfenadine and chlorpheniramine maleate in perennial rhinitis.

A double-blind clinical trial in 60 patients with perennial rhinitis was conducted to compare the efficacy and side effects of two antihistamines, terfenadine and chlorpheniramine maleate, and placebo. There was no statistically significant difference in response between active treatments and placebo. Although side effects were more frequent with chlorpheniramine this also was not statistically...

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An Experimental Study of the Anticonvulsant Effect of Chlorpheniramine Maleate in Mice

Objective: The need for the rational development of newer and adjuvant drugs to treat epilepsy has prompted this study of the potential anticonvulsant effect of chlorpheniramine maleate. Method The acute effect was studied in mice in single doses of 1 mg/kg, 2 mg/kg and 4 mg/kg of chlorpheniramine maleate and the chronic effect was studied in doses of 1 mg/kg and 4 mg/kg (administered daily for...

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ژورنال

عنوان ژورنال: Journal of Pain and Symptom Management

سال: 2004

ISSN: 0885-3924

DOI: 10.1016/j.jpainsymman.2004.02.004